Identification and characterization of sources of airborne antibiotic resistance genes in the urban environment using metagenomic approach
Presenta: Ying Yang
School of Marine Sciences, Sun Yat-Sen University, Guangzhou, China
Wide spread of antibiotic resistance genes (ARGs) has attracted increasing concern in recent years. However, the occurrence and diversity of ARGs in airborne particles remained to be understood. In this study, total suspended particles (TSPs) in the atmosphere from animal feedlots, wastewater treatment plant (WWTP), suburban and downtown area in Zhuhai (China) were analyzed for ARG profiles using metagenomic approaches. ARGs were abundant and diverse in TSP samples from animal feedlots and the WWTP. ARG profiles in the TSPs of feedlots were consistent with those in animal feces. Abundance and diversity of ARGs in downtown area was relatively lower compared with other TSPs samples with multidrug resistance genes as the most abundant ARG type. This study suggested that comprehensive profiles of ARGs could be helpful to displays a novel perspective on ARGs profiles in TSPs via metagenomic approach. Comprehensive analysis of the ARGs in airborne TSP could improve our understanding of ARGs dissemination pathways in the environment and their potential health threats.
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